Fgf-bp3 (Acc. No.CDB0444K) Fgf-bp3遺伝子のノックアウトマウス。Fgf-bp3は成体の前頭葉眼窩野に特異的に発現する遺伝子である。欠損マウスは新奇環境下で不安様行動を示す。 Phage P1 lox71 site, E. coli lacZ, rabbit beta-globin 3'pA, yeast FRT (flipase recombination target) sites, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, Phage P1 loxP site, mouse Pgk1 pA, mouse Fgfbp3 genomic DNA 条件を付加する。<br>(1) 分与希望者は事前に開発者 (京都大学、中畑　龍俊博士, E-mail: tnakaha@cira.kyoto-u.ac.jp) に連絡をとり、分与に関して許可を得ること。（2）当該マウスを用いる論文発表に際してはAcc.No. CDB0444K、そのWEB サイト（http://www2.clst.riken.jp/arg/mutant%20mice%20list.html）とともに当該マウスを記載すること。（3）当該マウスを用いる論文発表に際しては、その由来として第一報論文Mol Cell Neurosci. 2011 46(1):200-12.を引用すること。（4）発表論文を寄託者（mutant.bdr@riken.jp）に連絡すること。 (1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Tatsutoshi Nakahata, Kyoto University, E-mail: tnakaha@cira.kyoto-u.ac.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0444K and Web. Site (http://www2.clst.riken.jp/arg/mutant%20mice%20list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (Mol Cell Neurosci. 2011 46(1):200-12.) (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published. 京都大学大学院医学系研究科 中畑龍俊先生。 RBRC05277 B6.Cg-Fgfbp3<tm1Tohe>/Rbrc Developed by Tatsutoshi Nakahata, Graduate School of Medicine, Kyoto University. Heterozygote x Wild-type [C57BL/6N] Fgfbp3, fibroblast growth factor binding protein 3 knockout mice. Homozygous mutant mice show increased anxiety-related responses. FLP/frt system Cre/loxP system Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol> RIKEN CDB RIKEN CDB true C（3〜6か月） C (3-6 months) TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] Fgf-bp3 (Acc. No.CDB0444K) Fgf-bp3 (Acc. No.CDB0444K)